CHEMGRID MOLECULE CARD
ACEXAMIC ACID
ACEXAMIC ACID in ChemGrid: 192 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01503045
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01503045
- Molecular formula
- C8H15NO3
- InChIKey
- WDSCBUNMANHPFH-UHFFFAOYSA-N
- Libraries
- Spectrum, SPECMTS3
- Other recorded names
- 6-Acetylaminocaproic acid
Stored SMILES
CC(=O)NCCCCCC(O)=OMatched external records: PubChem 2005
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
192 measurements across 192 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ACHE · Acetylcholinesterase | ChEMBL | No stored yeast mapping |
| ADRA1A · Alpha-1A adrenergic receptor | ChEMBL | No stored yeast mapping |
| ADRA2A · Alpha-2A adrenergic receptor | ChEMBL | No stored yeast mapping |
| DRD1 · D(1A) dopamine receptor | ChEMBL | No stored yeast mapping |
| ESR1 · Estrogen receptor | ChEMBL | No stored yeast mapping |
| HDAC6 · Protein deacetylase HDAC6 | ChEMBL | HDA1 YNL021W (ortholog_one2one) |
| KCNH2 · Voltage-gated inwardly rectifying potassium channel KCNH2 | ChEMBL | No stored yeast mapping |
| rep · Replicase polyprotein 1ab | ChEMBL | No stored yeast mapping |
| SLC6A2 · Sodium-dependent noradrenaline transporter | ChEMBL | No stored yeast mapping |
| SLC6A3 · Sodium-dependent dopamine transporter | ChEMBL | No stored yeast mapping |
| SLC6A4 · Sodium-dependent serotonin transporter | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete ACEXAMIC ACID research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.