CHEMGRID MOLECULE CARD
BENZOIC ACID
BENZOIC ACID in ChemGrid: 104 screened assays, 4 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01503001
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01503001
- Molecular formula
- C7H6O2
- CAS registry number
- 65-85-0
- InChIKey
- WPYMKLBDIGXBTP-UHFFFAOYSA-N
- Libraries
- SPECMTS3, Spectrum_ED
- Other recorded names
- Benzoic Acid
Stored SMILES
OC(=O)c1ccccc1Matched external records: PubChem 243
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
104 measurements across 104 distinct library–species–strain assays; 4 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
| Strain | Library | Species identifier | Z-score |
|---|---|---|---|
| HOG1 | Spectrum_ED | 4932 | -5.93 |
| BY4743 | Spectrum_ED | 4932 | -4.33 |
| MKK1 | Spectrum_ED | 4932 | -4.02 |
| BY4741-2nd | Spectrum_ED | 4932 | -4.00 |
Spectrum compound-combination identifiers are excluded from this short table. The interactive profile retains the full measurements.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| DAO · D-amino-acid oxidase | ChEMBL | No stored yeast mapping |
| lef · Lethal factor | ChEMBL | No stored yeast mapping |
| Mmp9 · Matrix metalloproteinase-9 | ChEMBL | No stored yeast mapping |
| NAPRT · Nicotinate phosphoribosyltransferase | ChEMBL | NPT1 YOR209C (ortholog_one2many) |
| NEU3 · Sialidase-3 | ChEMBL | No stored yeast mapping |
| PPO2 · Mushroom tyrosinase | ChEMBL | No stored yeast mapping |
| Slc18a2 · Synaptic vesicular amine transporter | ChEMBL | TPO2 YGR138C (ortholog_many2many); TPO3 YPR156C (ortholog_many2many) |
| Slc22a20 · Solute carrier family 22 member 20 | ChEMBL | No stored yeast mapping |
| Slc22a6 · Solute carrier family 22 member 6 | ChEMBL | PHO84 YML123C (ortholog_one2many) |
| TSHR · Thyrotropin receptor | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete BENZOIC ACID research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.