CHEMGRID MOLECULE CARD
ELLAGIC ACID
ELLAGIC ACID in ChemGrid: 205 screened assays, 162 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01502245
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01502245
- Molecular formula
- C14H6O8
- CAS registry number
- 476-66-4
- InChIKey
- AFSDNFLWKVMVRB-UHFFFAOYSA-N
- Libraries
- Spectrum, SPECMTS3, Spectrum_ED
- Other recorded names
- Ellagic Acid
Stored SMILES
Oc1cc2C(=O)Oc3c(O)c(O)cc4C(=O)Oc(c1O)c2c34Matched external records: PubChem 5281855
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
205 measurements across 205 distinct library–species–strain assays; 162 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
| Strain | Library | Species identifier | Z-score |
|---|---|---|---|
| ssb2 | SPECMTS3 | 4932 | -30.55 |
| pop2 | Spectrum | 4932 | -29.79 |
| SLT2 | Spectrum | 4932 | -29.11 |
| ccr4 | SPECMTS3 | 4932 | -27.62 |
| arc18 | SPECMTS3 | 4932 | -26.03 |
| rvs167 | Spectrum | 4932 | -25.70 |
| snf2 | SPECMTS3 | 4932 | -25.53 |
| swi4 | SPECMTS3 | 4932 | -25.23 |
| kem1 | SPECMTS3 | 4932 | -24.02 |
| mad1 | Spectrum | 4932 | -23.81 |
| rpn1 | SPECMTS3 | 4932 | -23.45 |
| faa2 | SPECMTS3 | 4932 | -22.92 |
Spectrum compound-combination identifiers are excluded from this short table. The interactive profile retains the full measurements.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| APEX1 · DNA repair nuclease/redox regulator APEX1 | ChEMBL | No stored yeast mapping |
| CSNK2A1 · Casein kinase II subunit alpha | ChEMBL | CKA1 YIL035C (ortholog_many2many); CKA2 YOR061W (ortholog_many2many) |
| Csnk2b · Casein kinase 2 | ChEMBL | No stored yeast mapping |
| CSNK2B · Casein kinase II | ChEMBL | No stored yeast mapping |
| GPR35 · G-protein coupled receptor 35 | ChEMBL | No stored yeast mapping |
| Nt5e · 5'-nucleotidase | ChEMBL | YHR202W (ortholog_one2one) |
| PKLR · Pyruvate kinase PKLR | ChEMBL | CDC19 YAL038W (ortholog_many2many); PYK2 YOR347C (ortholog_many2many) |
| POLH · DNA polymerase eta | ChEMBL | RAD30 YDR419W (ortholog_one2one) |
| POLI · DNA polymerase iota | ChEMBL | No stored yeast mapping |
| RECQL · ATP-dependent DNA helicase Q1 | ChEMBL | No stored yeast mapping |
| TDP1 · Tyrosyl-DNA phosphodiesterase 1 | ChEMBL | TDP1 YBR223C (ortholog_one2one) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete ELLAGIC ACID research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.