ChemGrid

CHEMGRID MOLECULE CARD

RESVERATROL

RESVERATROL in ChemGrid: 616 screened assays, 35 with significant responses. Explore chemical identifiers, strain activity and target evidence.

SPE01502223

Explore activity & SONAR
Chemical structure of RESVERATROL
Stored molecular structure
616Screened assays
35Significant assay responses
35Source-labelled target records

Identity and chemistry

ChemGrid identifier
SPE01502223
Molecular formula
C14H12O3
CAS registry number
501-36-0
InChIKey
LUKBXSAWLPMMSZ-UHFFFAOYSA-N
Libraries
Spectrum, SPECMTS3, SpectrumTMP, Spectrum_ED
Other recorded names
5-(2-(4-Hydroxyphenyl)Ethenyl)Benzene-1,3-Diol
Stored SMILESOc1ccc(cc1)C=Cc1cc(O)cc(O)c1

Matched external records: PubChem 5056

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

616 measurements across 616 distinct library–species–strain assays; 35 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Up to 12 strongest recorded single-strain responses by absolute Z-score
StrainLibrarySpecies identifierZ-score
HAL24hSpectrumTMP4932-14.59
vps1Spectrum4932-12.21
Bck1Spectrum4932-11.59
FAS18hSpectrumTMP4932-11.53
DHA18hSpectrumTMP4932-11.07
rom2Spectrum4932-10.33
NIF18hSpectrumTMP4932-9.73
ser1Spectrum4932-8.54
rgp1SPECMTS34932-8.31
cdc73Spectrum4932-7.91
pop2Spectrum4932-7.81
mrt4Spectrum4932-7.37

Spectrum compound-combination identifiers are excluded from this short table. The interactive profile retains the full measurements.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
CA1 · Carbonic anhydrase 1ChEMBLNo stored yeast mapping
CA12 · Carbonic anhydrase 12ChEMBLNo stored yeast mapping
CA13 · Carbonic anhydrase 13ChEMBLNo stored yeast mapping
CA14 · Carbonic anhydrase 14ChEMBLNo stored yeast mapping
Ca15 · Carbonic anhydrase 15ChEMBLNo stored yeast mapping
CA2 · Carbonic anhydrase 2ChEMBLNo stored yeast mapping
CA3 · Carbonic anhydrase 3ChEMBLNo stored yeast mapping
CA4 · Carbonic anhydrase 4ChEMBLNo stored yeast mapping
CA5A · Carbonic anhydrase 5A, mitochondrialChEMBLNo stored yeast mapping
CA5B · Carbonic anhydrase 5B, mitochondrialChEMBLNo stored yeast mapping
CA6 · Carbonic anhydrase 6ChEMBLNo stored yeast mapping
CA7 · Carbonic anhydrase 7ChEMBLNo stored yeast mapping
ALK · ALK tyrosine kinase receptorChEMBL analogueNo stored yeast mapping
CA1 · Carbonic anhydrase 1ChEMBL analogueNo stored yeast mapping
CA12 · Carbonic anhydrase 12ChEMBL analogueNo stored yeast mapping
CA13 · Carbonic anhydrase 13ChEMBL analogueNo stored yeast mapping
CA14 · Carbonic anhydrase 14ChEMBL analogueNo stored yeast mapping
Ca15 · Carbonic anhydrase 15ChEMBL analogueNo stored yeast mapping
CA2 · Carbonic anhydrase 2ChEMBL analogueNo stored yeast mapping
CA3 · Carbonic anhydrase 3ChEMBL analogueNo stored yeast mapping
CA4 · Carbonic anhydrase 4ChEMBL analogueNo stored yeast mapping
CA5A · Carbonic anhydrase 5A, mitochondrialChEMBL analogueNo stored yeast mapping
CA5B · Carbonic anhydrase 5B, mitochondrialChEMBL analogueNo stored yeast mapping
CA6 · Carbonic anhydrase 6ChEMBL analogueNo stored yeast mapping
CAMKK2 · Calcium/calmodulin-dependent protein kinase kinase 2ChEMBL analogueSAK1 YER129W (ortholog_one2many); TOS3 YGL179C (ortholog_one2many)
DYRK1A · Dual specificity tyrosine-phosphorylation-regulated kinase 1AChEMBL analogueNo stored yeast mapping
DYRK1B · Dual specificity tyrosine-phosphorylation-regulated kinase 1BChEMBL analogueNo stored yeast mapping
MAP3K10 · Mitogen-activated protein kinase kinase kinase 10ChEMBL analogueNo stored yeast mapping
MAPK10 · Mitogen-activated protein kinase 10ChEMBL analogueNo stored yeast mapping
MARK3 · MAP/microtubule affinity-regulating kinase 3ChEMBL analogueNo stored yeast mapping

First 30 of 35 target records; open the interactive profile for further evidence.

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete RESVERATROL research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.