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CHEMGRID MOLECULE CARD

4-AMINO-3- (5-CHLOROTHIEN-2-YL)BUTANOIC ACID

4-AMINO-3- (5-CHLOROTHIEN-2-YL)BUTANOIC ACID in ChemGrid: 101 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

SPE01502143

Explore activity & SONAR
Chemical structure of 4-AMINO-3- (5-CHLOROTHIEN-2-YL)BUTANOIC ACID
Stored molecular structure
101Screened assays
0Significant assay responses
4Source-labelled target records

Identity and chemistry

ChemGrid identifier
SPE01502143
Molecular formula
C8ClH10NO2S
InChIKey
CDFQDLUHBLZCGL-UHFFFAOYSA-N
Libraries
Spectrum
Other recorded names
4-Amino-3-(5-chloro-2-thienyl)butyric acid
Stored SMILESNCC(CC(O)=O)c1sc(Cl)cc1

Matched external records: PubChem 125917

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

101 measurements across 101 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
APEX1 · DNA repair nuclease/redox regulator APEX1ChEMBLNo stored yeast mapping
Gabbr1 · GABA B receptorChEMBLNo stored yeast mapping
GABBR1 · GABA-B receptorChEMBLNo stored yeast mapping
Gabrp · GABA-A receptor; anion channelChEMBLNo stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete 4-AMINO-3- (5-CHLOROTHIEN-2-YL)BUTANOIC ACID research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.