ChemGrid

CHEMGRID MOLECULE CARD

SUCCINYLACETONE

SUCCINYLACETONE in ChemGrid: 104 screened assays, 1 with significant responses. Explore chemical identifiers, strain activity and target evidence.

SPE01502098

Explore activity & SONAR
Chemical structure of SUCCINYLACETONE
Stored molecular structure
104Screened assays
1Significant assay responses
2Source-labelled target records

Identity and chemistry

ChemGrid identifier
SPE01502098
Molecular formula
C7H10O4
CAS registry number
51568-18-4
InChIKey
WYEPBHZLDUPIOD-UHFFFAOYSA-N
Libraries
SPECMTS3, Spectrum_ED
Other recorded names
Succinylacetone
Stored SMILESCC(=O)CC(=O)CCC(O)=O

Matched external records: PubChem 5312

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

104 measurements across 104 distinct library–species–strain assays; 1 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Up to 12 strongest recorded single-strain responses by absolute Z-score
StrainLibrarySpecies identifierZ-score
pdr_yCG196Spectrum_ED4932-6.60

Spectrum compound-combination identifiers are excluded from this short table. The interactive profile retains the full measurements.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
KDM2A · Lysine-specific demethylase 2AChEMBLNo stored yeast mapping
PHF8 · Histone lysine demethylase PHF8ChEMBLNo stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete SUCCINYLACETONE research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.