ChemGrid

CHEMGRID MOLECULE CARD

LISINOPRIL

LISINOPRIL in ChemGrid: 205 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

SPE01501217

Explore activity & SONAR
Chemical structure of LISINOPRIL
Stored molecular structure
205Screened assays
0Significant assay responses
2Source-labelled target records

Identity and chemistry

ChemGrid identifier
SPE01501217
Molecular formula
C21H31N3O5
InChIKey
RLAWWYSOJDYHDC-UHFFFAOYSA-N
Libraries
Spectrum, SPECMTS3, Spectrum_ED
Other recorded names
1-{6-Amino-2-[(1-carboxy-3-phenylpropyl)amino]hexanoyl}pyrrolidine-2-carboxylic acid
Stored SMILESNCCCCC(NC(CCc1ccccc1)C(O)=O)C(=O)N1CCCC1C(O)=O

Matched external records: PubChem 3937

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

205 measurements across 205 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
ACE · Angiotensin-converting enzymeChEMBLNo stored yeast mapping
MAPT · Microtubule-associated protein tauChEMBLNo stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete LISINOPRIL research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.