CHEMGRID MOLECULE CARD
SULFAMONOMETHOXINE
SULFAMONOMETHOXINE in ChemGrid: 205 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01501147
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01501147
- Molecular formula
- C11H12N4O3S
- CAS registry number
- 1220-83-3
- InChIKey
- WMPXPUYPYQKQCX-UHFFFAOYSA-N
- Libraries
- Spectrum, SPECMTS3, Spectrum_ED
- Other recorded names
- Sulfamonomethoxine
Stored SMILES
COc1cc(NS(=O)(=O)c2ccc(N)cc2)ncn1Matched external records: PubChem 5332
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
205 measurements across 205 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL | SET2 YJL168C (ortholog_many2many) |
| HDAC6 · Protein deacetylase HDAC6 | ChEMBL | HDA1 YNL021W (ortholog_one2one) |
| PDCD1 · Programmed cell death protein 1/Programmed cell death 1 ligand 1 | ChEMBL | No stored yeast mapping |
| rep · Replicase polyprotein 1ab | ChEMBL | No stored yeast mapping |
| SAMHD1 · Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | ChEMBL | No stored yeast mapping |
| TDP1 · Tyrosyl-DNA phosphodiesterase 1 | ChEMBL | TDP1 YBR223C (ortholog_one2one) |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL analogue | SET2 YJL168C (ortholog_many2many) |
| HDAC6 · Protein deacetylase HDAC6 | ChEMBL analogue | HDA1 YNL021W (ortholog_one2one) |
| PDCD1 · Programmed cell death protein 1/Programmed cell death 1 ligand 1 | ChEMBL analogue | No stored yeast mapping |
| rep · Replicase polyprotein 1ab | ChEMBL analogue | No stored yeast mapping |
| SAMHD1 · Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | ChEMBL analogue | No stored yeast mapping |
| TDP1 · Tyrosyl-DNA phosphodiesterase 1 | ChEMBL analogue | TDP1 YBR223C (ortholog_one2one) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete SULFAMONOMETHOXINE research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.