CHEMGRID MOLECULE CARD
GLAFENINE
GLAFENINE in ChemGrid: 114 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01500996
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01500996
- Molecular formula
- C19ClH17N2O4
- CAS registry number
- 3820-67-5
- InChIKey
- GWOFUCIGLDBNKM-UHFFFAOYSA-N
- Libraries
- Spectrum, Spectrum_ED
- Other recorded names
- Glafenine
Stored SMILES
OCC(O)COC(=O)c1ccccc1Nc1ccnc2cc(Cl)ccc12Matched external records: PubChem 3474
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
114 measurements across 114 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ADORA3 · Adenosine receptor A3 | ChEMBL | No stored yeast mapping |
| ADRA1A · Alpha-1A adrenergic receptor | ChEMBL | No stored yeast mapping |
| CHRM1 · Muscarinic acetylcholine receptor M1 | ChEMBL | No stored yeast mapping |
| CHRM2 · Muscarinic acetylcholine receptor M2 | ChEMBL | No stored yeast mapping |
| Gabra1 · Gamma-aminobutyric acid receptor subunit alpha-1 | ChEMBL | No stored yeast mapping |
| KCNH2 · Voltage-gated inwardly rectifying potassium channel KCNH2 | ChEMBL | No stored yeast mapping |
| KDR · Vascular endothelial growth factor receptor 2 | ChEMBL | No stored yeast mapping |
| PDE4A · 3',5'-cyclic-AMP phosphodiesterase 4A | ChEMBL | No stored yeast mapping |
| PDE4D · 3',5'-cyclic-AMP phosphodiesterase 4D | ChEMBL | No stored yeast mapping |
| PTGS1 · Prostaglandin G/H synthase 1 | ChEMBL | No stored yeast mapping |
| SLC29A1 · Equilibrative nucleoside transporter 1 | ChEMBL | FUN26 YAL022C (ortholog_one2many) |
| TBXA2R · Thromboxane A2 receptor | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete GLAFENINE research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.