CHEMGRID MOLECULE CARD
S-ISOCORYDINE (+)
S-ISOCORYDINE (+) in ChemGrid: 205 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01500860
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01500860
- Molecular formula
- C20H23NO4
- CAS registry number
- 475-67-2
- InChIKey
- QELDJEKNFOQJOY-UHFFFAOYSA-N
- Libraries
- Spectrum, SPECMTS3, Spectrum_ED
- Other recorded names
- ISOCORYDINE (+); (+)-Isocorydine; Luteanine
Stored SMILES
COc1ccc2CC3N(C)CCc4cc(OC)c(OC)c(c34)c2c1OMatched external records: PubChem 10143 PubChem 48704
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
205 measurements across 205 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| SHMT2 · Serine hydroxymethyltransferase, mitochondrial | ChEMBL | SHM2 YLR058C (ortholog_one2many) |
| KAT2A · Histone acetyltransferase KAT2A | ChEMBL analogue | BDF2 YDL070W (ortholog_many2many); BDF1 YLR399C (ortholog_many2many) |
| MAPT · Microtubule-associated protein tau | ChEMBL analogue | No stored yeast mapping |
| Txnrd1 · Thioredoxin reductase 1, cytoplasmic | ChEMBL analogue | TRR1 YDR353W (ortholog_many2many); TRR2 YHR106W (ortholog_many2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete S-ISOCORYDINE (+) research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.