CHEMGRID MOLECULE CARD

BILIRUBIN

BILIRUBIN in ChemGrid: 205 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

SPE01500857

Explore activity & SONAR

Chemical structure of BILIRUBIN — Stored molecular structure

205Screened assays

0Significant assay responses

3Source-labelled target records

Identity and chemistry

ChemGrid identifier: SPE01500857
Molecular formula: C33H36N4O6
CAS registry number: 635-65-4
Libraries: Spectrum, SPECMTS3, Spectrum_ED
Other recorded names: Bilirubin

Stored SMILES

Cc1c(=O)nc(=Cc2nc(Cc3nc(C=c4nc(=O)c(C=C)c4C)c(C)c3CCC(O)=O)c(CCC(O)=O)c2C)c1C=C

Matched external records: PubChem 5280352

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

205 measurements across 205 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

Target	Source	Yeast ORF / orthologue
ffp · 4'-phosphopantetheinyl transferase ffp	ChEMBL	No stored yeast mapping
HSD17B10 · 3-hydroxyacyl-CoA dehydrogenase type-2	ChEMBL	No stored yeast mapping
MAPT · Microtubule-associated protein tau	ChEMBL	No stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete BILIRUBIN research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.