CHEMGRID MOLECULE CARD
3,4--DIMETHOXYFLAVONE
3,4--DIMETHOXYFLAVONE in ChemGrid: 13 screened assays, 2 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01500734
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01500734
- Molecular formula
- C17H14O4
- InChIKey
- AFIUIJXKXMMNCK-UHFFFAOYSA-N
- Libraries
- Spectrum_ED
- Other recorded names
- 3,4'-Dimethoxyflavone
Stored SMILES
COc1ccc(cc1)C1Oc2ccccc2C(=O)C=1OCMatched external records: PubChem 688666
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
13 measurements across 13 distinct library–species–strain assays; 2 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
| Strain | Library | Species identifier | Z-score |
|---|---|---|---|
| BY4743 | Spectrum_ED | 4932 | -5.00 |
| pdr_yCG196 | Spectrum_ED | 4932 | -4.32 |
Spectrum compound-combination identifiers are excluded from this short table. The interactive profile retains the full measurements.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ABCG2 · Broad substrate specificity ATP-binding cassette transporter ABCG2 | ChEMBL | SNQ2 YDR011W (ortholog_many2many); PDR15 YDR406W (ortholog_many2many); PDR11 YIL013C (ortholog_many2many); YNR070W (ortholog_many2many); AUS1 YOR011W (ortholog_many2many); PDR5 YOR153W (ortholog_many2many); PDR10 YOR328W (ortholog_many2many); PDR12 YPL058C (ortholog_many2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 3,4--DIMETHOXYFLAVONE research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.