CHEMGRID MOLECULE CARD
7,2--DIHYDROXYFLAVONE
7,2--DIHYDROXYFLAVONE in ChemGrid: 104 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01500719
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01500719
- Molecular formula
- C15H10O4
- CAS registry number
- 77298-66-9
- InChIKey
- NUGPQONICGTVNA-UHFFFAOYSA-N
- Libraries
- SPECMTS3, Spectrum_ED
- Other recorded names
- 7,2'-Dihydroxyflavone
Stored SMILES
Oc1ccc2C(=O)C=C(Oc2c1)c1ccccc1OMatched external records: PubChem 5391149
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
104 measurements across 104 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Akr1b1 · Aldo-keto reductase family 1 member B1 | ChEMBL | AAD3 YCR107W (ortholog_many2many); AAD4 YDL243C (ortholog_many2many); YPR1 YDR368W (ortholog_many2many); AAD10 YJR155W (ortholog_many2many); AAD14 YNL331C (ortholog_many2many); AAD15 YOL165C (ortholog_many2many); GCY1 YOR120W (ortholog_many2many) |
| ALOX15 · Polyunsaturated fatty acid lipoxygenase ALOX15 | ChEMBL | No stored yeast mapping |
| HPGD · 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | ChEMBL | AYR1 YIL124W (ortholog_one2one) |
| MEN1 · Menin/Histone-lysine N-methyltransferase MLL | ChEMBL | No stored yeast mapping |
| SMN1 · Survival motor neuron protein | ChEMBL | No stored yeast mapping |
| TP53 · Cellular tumor antigen p53 | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 7,2--DIHYDROXYFLAVONE research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.