CHEMGRID MOLECULE CARD
SULFAPYRIDINE
SULFAPYRIDINE in ChemGrid: 205 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01500551
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01500551
- Molecular formula
- C11H11N3O2S
- CAS registry number
- 144-83-2
- InChIKey
- GECHUMIMRBOMGK-UHFFFAOYSA-N
- Libraries
- Spectrum, SPECMTS3, Spectrum_ED
- Other recorded names
- Sulfapyridine
Stored SMILES
Nc1ccc(cc1)S(=O)(=O)Nc1ccccn1Matched external records: PubChem 5336
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
205 measurements across 205 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Cruzipain | ChEMBL | No stored yeast mapping |
| ampC · Beta-lactamase | ChEMBL | No stored yeast mapping |
| BAZ2B · Bromodomain adjacent to zinc finger domain protein 2B | ChEMBL | BDF2 YDL070W (ortholog_many2many); BDF1 YLR399C (ortholog_many2many) |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL | SET2 YJL168C (ortholog_many2many) |
| ffp · 4'-phosphopantetheinyl transferase ffp | ChEMBL | No stored yeast mapping |
| FTL · Ferritin light chain | ChEMBL | No stored yeast mapping |
| GMNN · Geminin | ChEMBL | No stored yeast mapping |
| NS1 · Nonstructural protein 1 | ChEMBL | No stored yeast mapping |
| PADI4 · Protein-arginine deiminase type-4 | ChEMBL | No stored yeast mapping |
| SLC7A11 · Cystine/glutamate transporter | ChEMBL | BAP2 YBR068C (ortholog_many2many); AGP1 YCL025C (ortholog_many2many); BAP3 YDR046C (ortholog_many2many); GNP1 YDR508C (ortholog_many2many); CAN1 YEL063C (ortholog_many2many); MMP1 YLL061W (ortholog_many2many); ALP1 YNL270C (ortholog_many2many); SAM3 YPL274W (ortholog_many2many) |
| SMN1 · Survival motor neuron protein | ChEMBL | No stored yeast mapping |
| Cruzipain | ChEMBL analogue | No stored yeast mapping |
| ampC · Beta-lactamase | ChEMBL analogue | No stored yeast mapping |
| BAZ2B · Bromodomain adjacent to zinc finger domain protein 2B | ChEMBL analogue | BDF2 YDL070W (ortholog_many2many); BDF1 YLR399C (ortholog_many2many) |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL analogue | SET2 YJL168C (ortholog_many2many) |
| ffp · 4'-phosphopantetheinyl transferase ffp | ChEMBL analogue | No stored yeast mapping |
| FTL · Ferritin light chain | ChEMBL analogue | No stored yeast mapping |
| GMNN · Geminin | ChEMBL analogue | No stored yeast mapping |
| NS1 · Nonstructural protein 1 | ChEMBL analogue | No stored yeast mapping |
| PADI4 · Protein-arginine deiminase type-4 | ChEMBL analogue | No stored yeast mapping |
| SLC7A11 · Cystine/glutamate transporter | ChEMBL analogue | BAP2 YBR068C (ortholog_many2many); AGP1 YCL025C (ortholog_many2many); BAP3 YDR046C (ortholog_many2many); GNP1 YDR508C (ortholog_many2many); CAN1 YEL063C (ortholog_many2many); MMP1 YLL061W (ortholog_many2many); ALP1 YNL270C (ortholog_many2many); SAM3 YPL274W (ortholog_many2many) |
| SMN1 · Survival motor neuron protein | ChEMBL analogue | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete SULFAPYRIDINE research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.