CHEMGRID MOLECULE CARD

PRIMAQUINE DIPHOSPHATE

PRIMAQUINE DIPHOSPHATE in ChemGrid: 205 screened assays, 1 with significant responses. Explore chemical identifiers, strain activity and target evidence.

SPE01500500

Explore activity & SONAR

Chemical structure of PRIMAQUINE DIPHOSPHATE — Stored molecular structure

205Screened assays

1Significant assay responses

6Source-labelled target records

Identity and chemistry

ChemGrid identifier: SPE01500500
Molecular formula: C15H27N3O9P2
InChIKey: GJOHLWZHWQUKAU-UHFFFAOYSA-N
Libraries: Spectrum, SPECMTS3, Spectrum_ED
Other recorded names: Primaquine Diphosphate

Stored SMILES

COc1cc(NC(C)CCCN)c2ncccc2c1.OP(O)(O)=O.OP(O)(O)=O

Matched external records: PubChem 6135

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

205 measurements across 205 distinct library–species–strain assays; 1 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Up to 12 strongest recorded single-strain responses by absolute Z-score
Strain	Library	Species identifier	Z-score
bem2	SPECMTS3	4932	-4.15

Spectrum compound-combination identifiers are excluded from this short table. The interactive profile retains the full measurements.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

Target	Source	Yeast ORF / orthologue
ATAD5 · ATPase family AAA domain-containing protein 5	ChEMBL	No stored yeast mapping
BAZ2B · Bromodomain adjacent to zinc finger domain protein 2B	ChEMBL	BDF2 YDL070W (ortholog_many2many); BDF1 YLR399C (ortholog_many2many)
CASP6 · Caspase-6	ChEMBL	No stored yeast mapping
EHMT2 · Histone-lysine N-methyltransferase EHMT2	ChEMBL	SET2 YJL168C (ortholog_many2many)
recA · Protein RecA	ChEMBL	RAD51 YER095W (ortholog_one2one)
USP1 · Ubiquitin carboxyl-terminal hydrolase 1	ChEMBL	UBP13 YBL067C (ortholog_many2many); UBP9 YER098W (ortholog_many2many); UBP8 YMR223W (ortholog_many2many); UBP2 YOR124C (ortholog_many2many)

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete PRIMAQUINE DIPHOSPHATE research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.