CHEMGRID MOLECULE CARD

METHOCARBAMOL

METHOCARBAMOL in ChemGrid: 205 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

SPE01500397

Explore activity & SONAR

Chemical structure of METHOCARBAMOL — Stored molecular structure

205Screened assays

0Significant assay responses

4Source-labelled target records

Identity and chemistry

ChemGrid identifier: SPE01500397
Molecular formula: C11H15NO5
CAS registry number: 532-03-6
InChIKey: GNXFOGHNGIVQEH-UHFFFAOYSA-N
Libraries: Spectrum, SPECMTS3, Spectrum_ED
Other recorded names: Methocarbamol

Stored SMILES

COc1ccccc1OCC(O)COC(N)=O

Matched external records: PubChem 4107

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

205 measurements across 205 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

Target	Source	Yeast ORF / orthologue
CBX1 · Chromobox protein homolog 1	ChEMBL	No stored yeast mapping
rep · Replicase polyprotein 1ab	ChEMBL	No stored yeast mapping
SMN1 · Survival motor neuron protein	ChEMBL	No stored yeast mapping
TARDBP · TAR DNA-binding protein 43	ChEMBL	PIN4 YBL051C (ortholog_many2many)

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete METHOCARBAMOL research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.