CHEMGRID MOLECULE CARD
ISOPROTERENOL HYDROCHLORIDE
ISOPROTERENOL HYDROCHLORIDE in ChemGrid: 205 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01500357
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01500357
- Molecular formula
- C11ClH18NO3
- InChIKey
- IROWCYIEJAOFOW-UHFFFAOYSA-N
- Libraries
- Spectrum, SPECMTS3, Spectrum_ED
- Other recorded names
- (+-)-Isoproterenol hydrochloride
Stored SMILES
Cl.CC(C)NCC(O)c1ccc(O)c(O)c1Matched external records: PubChem 5807
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
205 measurements across 205 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ADRB2 · Beta-2 adrenergic receptor | ChEMBL | No stored yeast mapping |
| ALDOA · Fructose-bisphosphate aldolase A | ChEMBL | No stored yeast mapping |
| BLM · RecQ-like DNA helicase BLM | ChEMBL | SGS1 YMR190C (ortholog_one2one) |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL | SET2 YJL168C (ortholog_many2many) |
| fba · Fructose-bisphosphate aldolase | ChEMBL | SMI1 YGR229C (ortholog_one2many) |
| GAA · Lysosomal alpha-glucosidase | ChEMBL | ROT2 YBR229C (ortholog_one2many) |
| HSD17B10 · 3-hydroxyacyl-CoA dehydrogenase type-2 | ChEMBL | No stored yeast mapping |
| MAPK1 · Mitogen-activated protein kinase 1 | ChEMBL | SLT2 YHR030C (ortholog_many2many); YKL161C (ortholog_many2many) |
| MAPT · Microtubule-associated protein tau | ChEMBL | No stored yeast mapping |
| RXFP1 · Relaxin receptor 1 | ChEMBL | No stored yeast mapping |
| TSHR · Thyrotropin receptor | ChEMBL | No stored yeast mapping |
| ADRA1A · Alpha-1A adrenergic receptor | ChEMBL analogue | No stored yeast mapping |
| ADRB2 · Beta-2 adrenergic receptor | ChEMBL analogue | No stored yeast mapping |
| ALDOA · Fructose-bisphosphate aldolase A | ChEMBL analogue | No stored yeast mapping |
| APEX1 · DNA repair nuclease/redox regulator APEX1 | ChEMBL analogue | No stored yeast mapping |
| ARSA · Arylsulfatase A | ChEMBL analogue | No stored yeast mapping |
| BLM · RecQ-like DNA helicase BLM | ChEMBL analogue | SGS1 YMR190C (ortholog_one2one) |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL analogue | SET2 YJL168C (ortholog_many2many) |
| fba · Fructose-bisphosphate aldolase | ChEMBL analogue | SMI1 YGR229C (ortholog_one2many) |
| GAA · Lysosomal alpha-glucosidase | ChEMBL analogue | ROT2 YBR229C (ortholog_one2many) |
| GLP1R · Glucagon-like peptide 1 receptor | ChEMBL analogue | No stored yeast mapping |
| GMNN · Geminin | ChEMBL analogue | No stored yeast mapping |
| HSD17B10 · 3-hydroxyacyl-CoA dehydrogenase type-2 | ChEMBL analogue | No stored yeast mapping |
| Htr2a · 5-hydroxytryptamine receptor 2A | ChEMBL analogue | No stored yeast mapping |
| KDM4E · Lysine-specific demethylase 4E | ChEMBL analogue | YJR119C (ortholog_one2many) |
| MAPK1 · Mitogen-activated protein kinase 1 | ChEMBL analogue | SLT2 YHR030C (ortholog_many2many); YKL161C (ortholog_many2many) |
| MAPT · Microtubule-associated protein tau | ChEMBL analogue | No stored yeast mapping |
| NPSR1 · Neuropeptide S receptor | ChEMBL analogue | No stored yeast mapping |
| NR0B1 · Nuclear receptor subfamily 0 group B member 1 | ChEMBL analogue | No stored yeast mapping |
| OPRM1 · Mu-type opioid receptor | ChEMBL analogue | No stored yeast mapping |
First 30 of 37 target records; open the interactive profile for further evidence.
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete ISOPROTERENOL HYDROCHLORIDE research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.