CHEMGRID MOLECULE CARD
ESTRADIOL CYPIONATE
ESTRADIOL CYPIONATE in ChemGrid: 205 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01500283
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01500283
- Molecular formula
- C26H36O3
- CAS registry number
- 313-06-4
- InChIKey
- UOACKFBJUYNSLK-UHFFFAOYSA-N
- Libraries
- Spectrum, SPECMTS3, Spectrum_ED
- Other recorded names
- 3-Hydroxyestra-1,3,5(10)-trien-17-yl 3-cyclopentylpropanoate
Stored SMILES
CC12CCC3C(CCc4cc(O)ccc34)C1CCC2OC(=O)CCC1CCCC1Matched external records: PubChem 3263
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
205 measurements across 205 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Cruzipain | ChEMBL analogue | No stored yeast mapping |
| ALOX15 · Polyunsaturated fatty acid lipoxygenase ALOX15 | ChEMBL analogue | No stored yeast mapping |
| ATXN2 · Ataxin-2 | ChEMBL analogue | No stored yeast mapping |
| BRCA1 · Breast cancer type 1 susceptibility protein | ChEMBL analogue | No stored yeast mapping |
| GMNN · Geminin | ChEMBL analogue | No stored yeast mapping |
| IDH1 · Isocitrate dehydrogenase [NADP] cytoplasmic | ChEMBL analogue | IDP1 YDL066W (ortholog_many2many); IDP2 YLR174W (ortholog_many2many); IDP3 YNL009W (ortholog_many2many) |
| LMNA · Prelamin-A/C | ChEMBL analogue | No stored yeast mapping |
| MAPK1 · Mitogen-activated protein kinase 1 | ChEMBL analogue | SLT2 YHR030C (ortholog_many2many); YKL161C (ortholog_many2many) |
| MEN1 · Menin/Histone-lysine N-methyltransferase MLL | ChEMBL analogue | No stored yeast mapping |
| NFE2L2 · Nuclear factor erythroid 2-related factor 2 | ChEMBL analogue | No stored yeast mapping |
| P4HB · Protein disulfide-isomerase | ChEMBL analogue | PDI1 YCL043C (ortholog_many2many); EUG1 YDR518W (ortholog_many2many) |
| PIN1 · Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | ChEMBL analogue | ESS1 YJR017C (ortholog_one2one) |
| RAPGEF3 · Rap guanine nucleotide exchange factor 3 | ChEMBL analogue | LTE1 YAL024C (ortholog_many2many); CDC25 YLR310C (ortholog_many2many) |
| RAPGEF4 · Rap guanine nucleotide exchange factor 4 | ChEMBL analogue | LTE1 YAL024C (ortholog_many2many) |
| RECQL · ATP-dependent DNA helicase Q1 | ChEMBL analogue | No stored yeast mapping |
| Rorc · Nuclear receptor ROR-gamma | ChEMBL analogue | No stored yeast mapping |
| SAMHD1 · Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | ChEMBL analogue | No stored yeast mapping |
| TDP1 · Tyrosyl-DNA phosphodiesterase 1 | ChEMBL analogue | TDP1 YBR223C (ortholog_one2one) |
| TSG101 · Tumor susceptibility gene 101 protein | ChEMBL analogue | STP22 YCL008C (ortholog_one2many) |
| USP1 · Ubiquitin carboxyl-terminal hydrolase 1 | ChEMBL analogue | UBP13 YBL067C (ortholog_many2many); UBP9 YER098W (ortholog_many2many); UBP8 YMR223W (ortholog_many2many); UBP2 YOR124C (ortholog_many2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete ESTRADIOL CYPIONATE research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.