CHEMGRID MOLECULE CARD
PYRITHIONE ZINC
PYRITHIONE ZINC in ChemGrid: 205 screened assays, 204 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01500260
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01500260
- Molecular formula
- C10H9N2O2S2Zn
- CAS registry number
- 13463-41-7
- Libraries
- Spectrum, SPECMTS3, Spectrum_ED
- Other recorded names
- 1-hydroxypyridine-2-thione;1-hydroxy-3H-pyridin-1-ium-2-thione;zinc
Stored SMILES
S=C1CC=CC=N1O[Zn]ON1C=CC=CC1=SMatched external records: PubChem 6327770
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
205 measurements across 205 distinct library–species–strain assays; 204 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
| Strain | Library | Species identifier | Z-score |
|---|---|---|---|
| BY4743 | Spectrum_ED | 4932 | -76.62 |
| nup100 | Spectrum | 4932 | -64.13 |
| elg1 | Spectrum | 4932 | -59.01 |
| BY4741 | SPECMTS3 | 4932 | -57.82 |
| BY4741-3rd | Spectrum_ED | 4932 | -57.40 |
| tub3 | Spectrum | 4932 | -55.93 |
| nat1 | SPECMTS3 | 4932 | -55.85 |
| kgd1 | Spectrum | 4932 | -55.16 |
| set2 | Spectrum | 4932 | -55.08 |
| pex11 | Spectrum | 4932 | -55.08 |
| paf1 | SPECMTS3 | 4932 | -54.50 |
| mdh1 | Spectrum | 4932 | -54.29 |
Spectrum compound-combination identifiers are excluded from this short table. The interactive profile retains the full measurements.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
Structural activity predictions and SONAR
Check the interactive profile for current structural prediction availability.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete PYRITHIONE ZINC research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.