CHEMGRID MOLECULE CARD
CYCLOPENTOLATE HYDROCHLORIDE
CYCLOPENTOLATE HYDROCHLORIDE in ChemGrid: 205 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE01500212
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE01500212
- Molecular formula
- C17ClH26NO3
- InChIKey
- RHKZVMUBMXGOLL-UHFFFAOYSA-N
- Libraries
- Spectrum, SPECMTS3, Spectrum_ED
- Other recorded names
- Cyclopentolate Hydrochloride
Stored SMILES
Cl.CN(C)CCOC(=O)C(c1ccccc1)C1(O)CCCC1Matched external records: PubChem 22162
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
205 measurements across 205 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Impa1 · Inositol monophosphatase 1 | ChEMBL | No stored yeast mapping |
| LMNA · Prelamin-A/C | ChEMBL | No stored yeast mapping |
| RAN · GTP-binding nuclear protein Ran/Importin subunit beta-1/Snurportin-1 | ChEMBL | GSP1 YLR293C (ortholog_one2many); GSP2 YOR185C (ortholog_one2many) |
| SMN1 · Survival motor neuron protein | ChEMBL | No stored yeast mapping |
| ATXN2 · Ataxin-2 | ChEMBL analogue | No stored yeast mapping |
| CBX1 · Chromobox protein homolog 1 | ChEMBL analogue | No stored yeast mapping |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL analogue | SET2 YJL168C (ortholog_many2many) |
| GLP1R · Glucagon-like peptide 1 receptor | ChEMBL analogue | No stored yeast mapping |
| HDAC6 · Protein deacetylase HDAC6 | ChEMBL analogue | HDA1 YNL021W (ortholog_one2one) |
| IDH1 · Isocitrate dehydrogenase [NADP] cytoplasmic | ChEMBL analogue | IDP1 YDL066W (ortholog_many2many); IDP2 YLR174W (ortholog_many2many); IDP3 YNL009W (ortholog_many2many) |
| KCNH2 · Voltage-gated inwardly rectifying potassium channel KCNH2 | ChEMBL analogue | No stored yeast mapping |
| MEN1 · Menin/Histone-lysine N-methyltransferase MLL | ChEMBL analogue | No stored yeast mapping |
| nfo · Endonuclease 4 | ChEMBL analogue | No stored yeast mapping |
| OPRD1 · Delta-type opioid receptor | ChEMBL analogue | No stored yeast mapping |
| OPRK1 · Kappa-type opioid receptor | ChEMBL analogue | No stored yeast mapping |
| rep · Replicase polyprotein 1ab | ChEMBL analogue | No stored yeast mapping |
| Rorc · Nuclear receptor ROR-gamma | ChEMBL analogue | No stored yeast mapping |
| SIGMAR1 · Sigma non-opioid intracellular receptor 1 | ChEMBL analogue | No stored yeast mapping |
| TDP1 · Tyrosyl-DNA phosphodiesterase 1 | ChEMBL analogue | TDP1 YBR223C (ortholog_one2one) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete CYCLOPENTOLATE HYDROCHLORIDE research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.