ChemGrid

CHEMGRID MOLECULE CARD

BACITRACIN

BACITRACIN in ChemGrid: 205 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

SPE01500134

Explore activity & SONAR
Chemical structure of BACITRACIN
Stored molecular structure
205Screened assays
0Significant assay responses
4Source-labelled target records

Identity and chemistry

ChemGrid identifier
SPE01500134
Molecular formula
C66H103N17O16S
CAS registry number
1405-87-4
Libraries
Spectrum, SPECMTS3, Spectrum_ED
Other recorded names
Bacitracin
Stored SMILESCCC(C)C(N)C1SCC(N=1)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(C(C)CC)C(=O)NCCCCC1NC(=O)C(CC(N)=O)NC(=O)C(CC(O)=O)NC(=O)C(Cc2cncn2)NC(=O)C(Cc2ccccc2)NC(=O)C(NC(=O)C(CCCN)NC1=O)C(C)CC

Matched external records: PubChem 10909430

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

205 measurements across 205 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
EGFR · Epidermal growth factor receptorChEMBLNo stored yeast mapping
Htr1b · 5-hydroxytryptamine receptor 1BChEMBLNo stored yeast mapping
LCK · Tyrosine-protein kinase LckChEMBLNo stored yeast mapping
uppP · Undecaprenyl-diphosphataseChEMBLNo stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete BACITRACIN research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.