ChemGrid

CHEMGRID MOLECULE CARD

ATRAZINE

ATRAZINE in ChemGrid: 205 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

SPE00330029

Explore activity & SONAR
Chemical structure of ATRAZINE
Stored molecular structure
205Screened assays
0Significant assay responses
27Source-labelled target records

Identity and chemistry

ChemGrid identifier
SPE00330029
Molecular formula
C8ClH14N5
CAS registry number
1912-24-9
InChIKey
MXWJVTOOROXGIU-UHFFFAOYSA-N
Libraries
Spectrum, SPECMTS3, Spectrum_ED
Other recorded names
Atrazine
Stored SMILESCCNc1nc(Cl)nc(NC(C)C)n1

Matched external records: PubChem 2256

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

205 measurements across 205 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
Chloroplast thylakoid membrane protein (psbA)ChEMBLNo stored yeast mapping
Luciferin 4-monooxygenaseChEMBLNo stored yeast mapping
GLP1R · Glucagon-like peptide 1 receptorChEMBLNo stored yeast mapping
GLS · Glutaminase kidney isoform, mitochondrialChEMBLNo stored yeast mapping
petD · Cytochrome b6-f complex subunit 4ChEMBLNo stored yeast mapping
POLI · DNA polymerase iotaChEMBLNo stored yeast mapping
PPARD · Peroxisome proliferator-activated receptor deltaChEMBLNo stored yeast mapping
psbA · Photosystem Q(B) proteinChEMBLNo stored yeast mapping
Rorc · Nuclear receptor ROR-gammaChEMBLNo stored yeast mapping
Chloroplast thylakoid membrane protein (psbA)ChEMBL analogueNo stored yeast mapping
Luciferin 4-monooxygenaseChEMBL analogueNo stored yeast mapping
APEX1 · DNA repair nuclease/redox regulator APEX1ChEMBL analogueNo stored yeast mapping
FTL · Ferritin light chainChEMBL analogueNo stored yeast mapping
GAA · Lysosomal alpha-glucosidaseChEMBL analogueROT2 YBR229C (ortholog_one2many)
GLP1R · Glucagon-like peptide 1 receptorChEMBL analogueNo stored yeast mapping
GLS · Glutaminase kidney isoform, mitochondrialChEMBL analogueNo stored yeast mapping
KAT2A · Histone acetyltransferase KAT2AChEMBL analogueBDF2 YDL070W (ortholog_many2many); BDF1 YLR399C (ortholog_many2many)
LMNA · Prelamin-A/CChEMBL analogueNo stored yeast mapping
petD · Cytochrome b6-f complex subunit 4ChEMBL analogueNo stored yeast mapping
POLI · DNA polymerase iotaChEMBL analogueNo stored yeast mapping
POLK · DNA polymerase kappaChEMBL analogueTRF5 YNL299W (ortholog_many2many); PAP2 YOL115W (ortholog_many2many)
PPARD · Peroxisome proliferator-activated receptor deltaChEMBL analogueNo stored yeast mapping
PPX1 · Protoporphyrinogen IX oxidaseChEMBL analogueNo stored yeast mapping
psbA · Photosystem Q(B) proteinChEMBL analogueNo stored yeast mapping
Rorc · Nuclear receptor ROR-gammaChEMBL analogueNo stored yeast mapping
TDP1 · Tyrosyl-DNA phosphodiesterase 1ChEMBL analogueTDP1 YBR223C (ortholog_one2one)
THRB · Thyroid hormone receptor betaChEMBL analogueNo stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete ATRAZINE research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.