CHEMGRID MOLECULE CARD
CHLORQUINALDOL
CHLORQUINALDOL in ChemGrid: 91 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE00212151
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE00212151
- Molecular formula
- C10Cl2H7NO
- CAS registry number
- 72-80-0
- InChIKey
- GPTXWRGISTZRIO-UHFFFAOYSA-N
- Libraries
- SPECMTS3
- Other recorded names
- Chlorquinaldol
Stored SMILES
Cc1ccc2c(Cl)cc(Cl)c(O)c2n1Matched external records: PubChem 6301
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
91 measurements across 91 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| APE1 · Vacuolar aminopeptidase 1 | ChEMBL | APN2 YBL019W (ortholog_one2many) |
| CGA · Glycoprotein hormones alpha chain | ChEMBL | No stored yeast mapping |
| GMNN · Geminin | ChEMBL | No stored yeast mapping |
| HSPA5 · Endoplasmic reticulum chaperone BiP | ChEMBL | No stored yeast mapping |
| MAPT · Microtubule-associated protein tau | ChEMBL | No stored yeast mapping |
| POLI · DNA polymerase iota | ChEMBL | No stored yeast mapping |
| Rorc · Nuclear receptor ROR-gamma | ChEMBL | No stored yeast mapping |
| RPL19A · Large ribosomal subunit protein eL19A | ChEMBL | No stored yeast mapping |
| SMAD3 · Mothers against decapentaplegic homolog 3 | ChEMBL | No stored yeast mapping |
| TARDBP · TAR DNA-binding protein 43 | ChEMBL | PIN4 YBL051C (ortholog_many2many) |
| TDP1 · Tyrosyl-DNA phosphodiesterase 1 | ChEMBL | TDP1 YBR223C (ortholog_one2one) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete CHLORQUINALDOL research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.