CHEMGRID MOLECULE CARD
PHENYLACETOHYDROXAMIC ACID
PHENYLACETOHYDROXAMIC ACID in ChemGrid: 91 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE00210031
Explore activity & SONARIdentity and chemistry
- ChemGrid identifier
- SPE00210031
- Molecular formula
- C8H9NO2
- InChIKey
- FPOQLQZHRCEVOT-UHFFFAOYSA-N
- Libraries
- SPECMTS3
- Other recorded names
- N-hydroxy-2-phenylacetamide
Stored SMILES
ONC(=O)Cc1ccccc1Matched external records: PubChem 220184
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
91 measurements across 91 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Alox5 · Polyunsaturated fatty acid 5-lipoxygenase | ChEMBL | No stored yeast mapping |
| HDAC1 · Histone deacetylase | ChEMBL | No stored yeast mapping |
| HDAC2 · Histone deacetylase 2 | ChEMBL | No stored yeast mapping |
| HDAC4 · Histone deacetylase 4 | ChEMBL | No stored yeast mapping |
| HDAC6 · Protein deacetylase HDAC6 | ChEMBL | HDA1 YNL021W (ortholog_one2one) |
| HDAC8 · Histone deacetylase 8 | ChEMBL | No stored yeast mapping |
| lasB · Elastase | ChEMBL | No stored yeast mapping |
| MEN1 · Menin/Histone-lysine N-methyltransferase MLL | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete PHENYLACETOHYDROXAMIC ACID research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.