ChemGrid

CHEMGRID MOLECULE CARD

PHENYLACETOHYDROXAMIC ACID

PHENYLACETOHYDROXAMIC ACID in ChemGrid: 91 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

SPE00210031

Explore activity & SONAR
Chemical structure of PHENYLACETOHYDROXAMIC ACID
Stored molecular structure
91Screened assays
0Significant assay responses
8Source-labelled target records

Identity and chemistry

ChemGrid identifier
SPE00210031
Molecular formula
C8H9NO2
InChIKey
FPOQLQZHRCEVOT-UHFFFAOYSA-N
Libraries
SPECMTS3
Other recorded names
N-hydroxy-2-phenylacetamide
Stored SMILESONC(=O)Cc1ccccc1

Matched external records: PubChem 220184

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

91 measurements across 91 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
Alox5 · Polyunsaturated fatty acid 5-lipoxygenaseChEMBLNo stored yeast mapping
HDAC1 · Histone deacetylaseChEMBLNo stored yeast mapping
HDAC2 · Histone deacetylase 2ChEMBLNo stored yeast mapping
HDAC4 · Histone deacetylase 4ChEMBLNo stored yeast mapping
HDAC6 · Protein deacetylase HDAC6ChEMBLHDA1 YNL021W (ortholog_one2one)
HDAC8 · Histone deacetylase 8ChEMBLNo stored yeast mapping
lasB · ElastaseChEMBLNo stored yeast mapping
MEN1 · Menin/Histone-lysine N-methyltransferase MLLChEMBLNo stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete PHENYLACETOHYDROXAMIC ACID research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.