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CHEMGRID MOLECULE CARD

EPIAFZELECHIN (2R,3R)(-)

EPIAFZELECHIN (2R,3R)(-) in ChemGrid: 104 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

SPE00202178

Explore activity & SONAR
Chemical structure of EPIAFZELECHIN (2R,3R)(-)
Stored molecular structure
104Screened assays
0Significant assay responses
3Source-labelled target records

Identity and chemistry

ChemGrid identifier
SPE00202178
Molecular formula
C15H14O5
CAS registry number
24808-04-6
InChIKey
RSYUFYQTACJFML-UHFFFAOYSA-N
Libraries
SPECMTS3, Spectrum_ED
Other recorded names
2-(4-Hydroxyphenyl)-3,4-Dihydro-2H-Chromene-3,5,7-Triol
Stored SMILESOC1Cc2c(O)cc(O)cc2OC1c1ccc(O)cc1

Matched external records: PubChem 282014

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

104 measurements across 104 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
ALK · ALK tyrosine kinase receptorChEMBLNo stored yeast mapping
MEN1 · Menin/Histone-lysine N-methyltransferase MLLChEMBLNo stored yeast mapping
POLK · DNA polymerase kappaChEMBLTRF5 YNL299W (ortholog_many2many); PAP2 YOL115W (ortholog_many2many)

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete EPIAFZELECHIN (2R,3R)(-) research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.