CHEMGRID MOLECULE CARD
7-DESHYDROXYPYROGALLIN-4-CARBOXYLIC ACID
7-DESHYDROXYPYROGALLIN-4-CARBOXYLIC ACID in ChemGrid: 205 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE00201508
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE00201508
- Molecular formula
- C12H8O6
- InChIKey
- XCSLJQFPTAZKDV-UHFFFAOYSA-N
- Libraries
- Spectrum, SPECMTS3, Spectrum_ED
- Other recorded names
- Shp2-IN-5
Stored SMILES
OC(=O)C1C=C(O)C(=O)c2c(O)c(O)ccc2C=1Matched external records: PubChem 153273978
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
205 measurements across 205 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ATG4B · Cysteine protease ATG4B | ChEMBL | ATG4 YNL223W (ortholog_one2many) |
| GPR35 · G-protein coupled receptor 35 | ChEMBL | No stored yeast mapping |
| groL · GroEL/GroES | ChEMBL | No stored yeast mapping |
| PTPN11 · Tyrosine-protein phosphatase non-receptor type 11 | ChEMBL | PTP3 YER075C (ortholog_many2many) |
| RNASEH1 · Ribonuclease H1 | ChEMBL | RNH1 YMR234W (ortholog_one2one) |
| Tlr2 · Toll-like receptor 1/2 | ChEMBL | No stored yeast mapping |
| ALOX15 · Polyunsaturated fatty acid lipoxygenase ALOX15 | ChEMBL analogue | No stored yeast mapping |
| APEX1 · DNA repair nuclease/redox regulator APEX1 | ChEMBL analogue | No stored yeast mapping |
| BLM · RecQ-like DNA helicase BLM | ChEMBL analogue | SGS1 YMR190C (ortholog_one2one) |
| fba · Fructose-bisphosphate aldolase | ChEMBL analogue | SMI1 YGR229C (ortholog_one2many) |
| HPGD · 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | ChEMBL analogue | AYR1 YIL124W (ortholog_one2one) |
| HSD17B10 · 3-hydroxyacyl-CoA dehydrogenase type-2 | ChEMBL analogue | No stored yeast mapping |
| MAPT · Microtubule-associated protein tau | ChEMBL analogue | No stored yeast mapping |
| POLK · DNA polymerase kappa | ChEMBL analogue | TRF5 YNL299W (ortholog_many2many); PAP2 YOL115W (ortholog_many2many) |
| PTPN11 · Tyrosine-protein phosphatase non-receptor type 11 | ChEMBL analogue | PTP3 YER075C (ortholog_many2many) |
| TDP1 · Tyrosyl-DNA phosphodiesterase 1 | ChEMBL analogue | TDP1 YBR223C (ortholog_one2one) |
| VDR · Vitamin D3 receptor | ChEMBL analogue | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 7-DESHYDROXYPYROGALLIN-4-CARBOXYLIC ACID research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.