CHEMGRID MOLECULE CARD
PINOSYLVIN
PINOSYLVIN in ChemGrid: 101 screened assays, 1 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE00201066
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE00201066
- Molecular formula
- C14H12O2
- InChIKey
- YCVPRTHEGLPYPB-UHFFFAOYSA-N
- Libraries
- Spectrum
- Other recorded names
- 5-Styrylresorcinol
Stored SMILES
Oc1cc(O)cc(C=Cc2ccccc2)c1Matched external records: PubChem 100754
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
101 measurements across 101 distinct library–species–strain assays; 1 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
| Strain | Library | Species identifier | Z-score |
|---|---|---|---|
| cdc73 | Spectrum | 4932 | -5.11 |
Spectrum compound-combination identifiers are excluded from this short table. The interactive profile retains the full measurements.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ALK · ALK tyrosine kinase receptor | ChEMBL analogue | No stored yeast mapping |
| CA1 · Carbonic anhydrase 1 | ChEMBL analogue | No stored yeast mapping |
| CA12 · Carbonic anhydrase 12 | ChEMBL analogue | No stored yeast mapping |
| CA13 · Carbonic anhydrase 13 | ChEMBL analogue | No stored yeast mapping |
| CA14 · Carbonic anhydrase 14 | ChEMBL analogue | No stored yeast mapping |
| Ca15 · Carbonic anhydrase 15 | ChEMBL analogue | No stored yeast mapping |
| CA2 · Carbonic anhydrase 2 | ChEMBL analogue | No stored yeast mapping |
| CA3 · Carbonic anhydrase 3 | ChEMBL analogue | No stored yeast mapping |
| CA4 · Carbonic anhydrase 4 | ChEMBL analogue | No stored yeast mapping |
| CA5A · Carbonic anhydrase 5A, mitochondrial | ChEMBL analogue | No stored yeast mapping |
| CA5B · Carbonic anhydrase 5B, mitochondrial | ChEMBL analogue | No stored yeast mapping |
| CA6 · Carbonic anhydrase 6 | ChEMBL analogue | No stored yeast mapping |
| CAMKK2 · Calcium/calmodulin-dependent protein kinase kinase 2 | ChEMBL analogue | SAK1 YER129W (ortholog_one2many); TOS3 YGL179C (ortholog_one2many) |
| DYRK1A · Dual specificity tyrosine-phosphorylation-regulated kinase 1A | ChEMBL analogue | No stored yeast mapping |
| DYRK1B · Dual specificity tyrosine-phosphorylation-regulated kinase 1B | ChEMBL analogue | No stored yeast mapping |
| MAP3K10 · Mitogen-activated protein kinase kinase kinase 10 | ChEMBL analogue | No stored yeast mapping |
| MAPK10 · Mitogen-activated protein kinase 10 | ChEMBL analogue | No stored yeast mapping |
| MARK3 · MAP/microtubule affinity-regulating kinase 3 | ChEMBL analogue | No stored yeast mapping |
| MARK4 · MAP/microtubule affinity-regulating kinase 4 | ChEMBL analogue | No stored yeast mapping |
| MELK · Maternal embryonic leucine zipper kinase | ChEMBL analogue | YPL150W (ortholog_one2one) |
| ROCK2 · Rho-associated protein kinase 2 | ChEMBL analogue | No stored yeast mapping |
| SIK2 · Serine/threonine-protein kinase SIK2 | ChEMBL analogue | PRR2 YDL214C (ortholog_many2many); KIN1 YDR122W (ortholog_many2many); VHS1 YDR247W (ortholog_many2many); HAL5 YJL165C (ortholog_many2many); PTK2 YJR059W (ortholog_many2many); KKQ8 YKL168C (ortholog_many2many); PTK1 YKL198C (ortholog_many2many); KIN2 YLR096W (ortholog_many2many); NPR1 YNL183C (ortholog_many2many); KIN4 YOR233W (ortholog_many2many); SKS1 YPL026C (ortholog_many2many); YPL141C (ortholog_many2many) |
| TYRO3 · Tyrosine-protein kinase receptor TYRO3 | ChEMBL analogue | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete PINOSYLVIN research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.