CHEMGRID MOLECULE CARD
HETEROPEUCENIN, METHYL ETHER
HETEROPEUCENIN, METHYL ETHER in ChemGrid: 616 screened assays, 85 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SPE00100529
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SPE00100529
- Molecular formula
- C16H18O4
- CAS registry number
- 26213-95-6
- InChIKey
- KVNRDSLYCOJCRD-UHFFFAOYSA-N
- Libraries
- Spectrum, SPECMTS3, SpectrumTMP, Spectrum_ED
- Other recorded names
- Heteropeucenin, methyl ether
Stored SMILES
COc1cc(O)c2C(=O)C=C(C)Oc2c1CC=C(C)CMatched external records: PubChem 4643333
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
616 measurements across 616 distinct library–species–strain assays; 85 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
| Strain | Library | Species identifier | Z-score |
|---|---|---|---|
| HAL24h | SpectrumTMP | 4932 | -27.96 |
| DHA18h | SpectrumTMP | 4932 | -19.02 |
| FAS18h | SpectrumTMP | 4932 | -18.85 |
| NIF18h | SpectrumTMP | 4932 | -16.38 |
| mck1 | Spectrum | 4932 | -16.24 |
| AVM18h | SpectrumTMP | 4932 | -14.10 |
| ser1 | Spectrum | 4932 | -13.01 |
| pex11 | Spectrum | 4932 | -10.58 |
| tif3 | Spectrum | 4932 | -10.51 |
| mcm21 | Spectrum | 4932 | -9.61 |
| DAM18h | SpectrumTMP | 4932 | -9.46 |
| cdc73 | Spectrum | 4932 | -9.35 |
Spectrum compound-combination identifiers are excluded from this short table. The interactive profile retains the full measurements.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ffp · 4'-phosphopantetheinyl transferase ffp | ChEMBL | No stored yeast mapping |
| KDM4E · Lysine-specific demethylase 4E | ChEMBL | YJR119C (ortholog_one2many) |
| USP1 · Ubiquitin carboxyl-terminal hydrolase 1 | ChEMBL | UBP13 YBL067C (ortholog_many2many); UBP9 YER098W (ortholog_many2many); UBP8 YMR223W (ortholog_many2many); UBP2 YOR124C (ortholog_many2many) |
| USP2 · Ubiquitin carboxyl-terminal hydrolase 2 | ChEMBL | UBP13 YBL067C (ortholog_many2many); UBP9 YER098W (ortholog_many2many) |
| APEX1 · DNA repair nuclease/redox regulator APEX1 | ChEMBL analogue | No stored yeast mapping |
| fba · Fructose-bisphosphate aldolase | ChEMBL analogue | SMI1 YGR229C (ortholog_one2many) |
| HPGD · 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | ChEMBL analogue | AYR1 YIL124W (ortholog_one2one) |
| MAPT · Microtubule-associated protein tau | ChEMBL analogue | No stored yeast mapping |
| TDP1 · Tyrosyl-DNA phosphodiesterase 1 | ChEMBL analogue | TDP1 YBR223C (ortholog_one2one) |
| TP53 · Cellular tumor antigen p53 | ChEMBL analogue | No stored yeast mapping |
| VDR · Vitamin D3 receptor | ChEMBL analogue | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete HETEROPEUCENIN, METHYL ETHER research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.