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CHEMGRID MOLECULE CARD

[4-(4-chlorophenyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl](cyclopropyl)methanone

[4-(4-chlorophenyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl](cyclopropyl)methanone in ChemGrid: 18 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

SEW 01036

Explore activity & SONAR
Chemical structure of [4-(4-chlorophenyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl](cyclopropyl)methanone
Stored molecular structure
18Screened assays
0Significant assay responses
1Source-labelled target records

Identity and chemistry

ChemGrid identifier
SEW 01036
Molecular formula
C17ClH16NOS
InChIKey
RJGSCKOJCQHSQB-UHFFFAOYSA-N
Libraries
Maybridge, Cytotoxic
Other recorded names
RJGSCKOJCQHSQB-UHFFFAOYSA-N
Stored SMILESClc1ccc(cc1)C1N(CCc2sccc12)C(=O)C1CC1

Matched external records: PubChem 2739312

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

18 measurements across 18 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
RAPGEF4 · Rap guanine nucleotide exchange factor 4ChEMBLLTE1 YAL024C (ortholog_many2many)

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete [4-(4-chlorophenyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl](cyclopropyl)methanone research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.