CHEMGRID MOLECULE CARD
fluoranthene
fluoranthene in ChemGrid: 50 screened assays, 39 with significant responses. Explore chemical identifiers, strain activity and target evidence.
SB 00542
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- SB 00542
- Molecular formula
- C16H10
- InChIKey
- GVEPBJHOBDJJJI-UHFFFAOYSA-N
- Libraries
- Maybridge1000
- Other recorded names
- Fluoranthene
Stored SMILES
c1ccc2c(c1)c1cccc3cccc2c31Matched external records: PubChem 9154
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
50 measurements across 50 distinct library–species–strain assays; 39 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
| Strain | Library | Species identifier | Z-score |
|---|---|---|---|
| MT2481-Camptothecin | Maybridge1000 | 4932 | -18.29 |
| But24 | Maybridge1000 | 4932 | -18.20 |
| CHRA24 | Maybridge1000 | 4932 | -17.25 |
| ypt6 | Maybridge1000 | 4932 | -15.02 |
| CNB1 | Maybridge1000 | 4932 | -13.29 |
| MT2481-pdr1pdr3 | Maybridge1000 | 4932 | -13.25 |
| arp6 | Maybridge1000 | 4932 | -12.33 |
| ric1 | Maybridge1000 | 4932 | -12.32 |
| cin2-2nd | Maybridge1000 | 4932 | -9.92 |
| Alg12 | Maybridge1000 | 4932 | -9.88 |
| WT-Fen | Maybridge1000 | 4932 | -9.40 |
| cin8 | Maybridge1000 | 4932 | -9.33 |
Spectrum compound-combination identifiers are excluded from this short table. The interactive profile retains the full measurements.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ATM · Serine-protein kinase ATM | ChEMBL | No stored yeast mapping |
| BAZ2B · Bromodomain adjacent to zinc finger domain protein 2B | ChEMBL | BDF2 YDL070W (ortholog_many2many); BDF1 YLR399C (ortholog_many2many) |
| CBX1 · Chromobox protein homolog 1 | ChEMBL | No stored yeast mapping |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL | SET2 YJL168C (ortholog_many2many) |
| GNAS · Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | ChEMBL | GPA2 YER020W (ortholog_many2many); GPA1 YHR005C (ortholog_many2many) |
| KDM4A · Lysine-specific demethylase 4A | ChEMBL | YJR119C (ortholog_one2many) |
| L3MBTL1 · Lethal(3)malignant brain tumor-like protein 1 | ChEMBL | No stored yeast mapping |
| lef · Lethal factor | ChEMBL | No stored yeast mapping |
| NFE2L2 · Nuclear factor erythroid 2-related factor 2 | ChEMBL | No stored yeast mapping |
| SMPD1 · Sphingomyelin phosphodiesterase | ChEMBL | PPN1 YDR452W (ortholog_one2many) |
| Txnrd1 · Thioredoxin reductase 1, cytoplasmic | ChEMBL | TRR1 YDR353W (ortholog_many2many); TRR2 YHR106W (ortholog_many2many) |
| AHR · Aryl hydrocarbon receptor | ChEMBL analogue | No stored yeast mapping |
| CBX1 · Chromobox protein homolog 1 | ChEMBL analogue | No stored yeast mapping |
| CYP1A2 · Cytochrome P450 1A2 | ChEMBL analogue | No stored yeast mapping |
| KDM4A · Lysine-specific demethylase 4A | ChEMBL analogue | YJR119C (ortholog_one2many) |
| POLI · DNA polymerase iota | ChEMBL analogue | No stored yeast mapping |
| SMAD3 · Mothers against decapentaplegic homolog 3 | ChEMBL analogue | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete fluoranthene research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.