CHEMGRID MOLECULE CARD
2-[(4-morpholinoanilino)methyl]isoindoline-1,3-dione
2-[(4-morpholinoanilino)methyl]isoindoline-1,3-dione in ChemGrid: 50 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
S 04546
Explore activity & SONAR![Chemical structure of 2-[(4-morpholinoanilino)methyl]isoindoline-1,3-dione](/structure-thumbnails/Maybridge1000/S_/S_04546.svg?v=2026-09-22T13%3A54%3A31%2B00%3A00)
Identity and chemistry
- ChemGrid identifier
- S 04546
- Molecular formula
- C19H19N3O3
- InChIKey
- NMFDNVJXDZBLQR-UHFFFAOYSA-N
- Libraries
- Maybridge1000
- Other recorded names
- N-(4-Morpholinoanilinomethyl)phthalimide
Stored SMILES
O=c1n(CNc2ccc(cc2)N2CCOCC2)c(=O)c2ccccc12Matched external records: PubChem 2731384
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
50 measurements across 50 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| RPS6KA2 · Ribosomal protein S6 kinase alpha-2 | ChEMBL | YBR028C (ortholog_many2many); KIN82 YCR091W (ortholog_many2many); YNR047W (ortholog_many2many) |
| RPS6KA3 · Ribosomal protein S6 kinase alpha-3 | ChEMBL | YBR028C (ortholog_many2many); KIN82 YCR091W (ortholog_many2many); YNR047W (ortholog_many2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 2-[(4-morpholinoanilino)methyl]isoindoline-1,3-dione research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.