CHEMGRID MOLECULE CARD
ethyl 4-hydroxy-2-phenylquinoline-6-carboxylate
ethyl 4-hydroxy-2-phenylquinoline-6-carboxylate in ChemGrid: 50 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
RH 02104
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- RH 02104
- Molecular formula
- C18H15NO3
- InChIKey
- MGUKTDNBGKTMHQ-UHFFFAOYSA-N
- Libraries
- Maybridge1000
- Other recorded names
- GNF-Pf-4475
Stored SMILES
CCOC(=O)c1ccc2nc(cc(O)c2c1)c1ccccc1Matched external records: PubChem 2728441
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
50 measurements across 50 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Lysine--tRNA ligase | ChEMBL | No stored yeast mapping |
| CDPK1 · Calcium-dependent protein kinase 1 | ChEMBL | No stored yeast mapping |
| CDPK4 · Calcium-dependent protein kinase 4 | ChEMBL | No stored yeast mapping |
| map-2 · Mitogen-activated protein kinase | ChEMBL | No stored yeast mapping |
| PK6 · Cdk-related protein kinase 6 | ChEMBL | No stored yeast mapping |
| pk7 · Putative uncharacterized protein pk7 | ChEMBL | No stored yeast mapping |
| proRS · Proline--tRNA ligase | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete ethyl 4-hydroxy-2-phenylquinoline-6-carboxylate research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.