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CHEMGRID MOLECULE CARD

N1-[3,5-di(trifluoromethyl)phenyl]-2-phenyl-2-(2-pyridylthio)acetamide

N1-[3,5-di(trifluoromethyl)phenyl]-2-phenyl-2-(2-pyridylthio)acetamide in ChemGrid: 50 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

RF 00256

Explore activity & SONAR
Chemical structure of N1-[3,5-di(trifluoromethyl)phenyl]-2-phenyl-2-(2-pyridylthio)acetamide
Stored molecular structure
50Screened assays
0Significant assay responses
0Source-labelled target records

Identity and chemistry

ChemGrid identifier
RF 00256
Molecular formula
C21F6H14N2OS
InChIKey
JCLPCQTUUSVALA-UHFFFAOYSA-N
Libraries
Maybridge1000
Other recorded names
N-[3,5-bis(trifluoromethyl)phenyl]-2-phenyl-2-pyridin-2-ylsulfanylacetamide
Stored SMILESFC(F)(F)c1cc(NC(=O)C(Sc2ccccn2)c2ccccc2)cc(c1)C(F)(F)F

Matched external records: PubChem 2726088

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

50 measurements across 50 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

No source-labelled target annotations are stored for this identifier in this snapshot. This does not mean the molecule has no biological targets.

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete N1-[3,5-di(trifluoromethyl)phenyl]-2-phenyl-2-(2-pyridylthio)acetamide research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.