CHEMGRID MOLECULE CARD
Racecadotril
Racecadotril in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
Prest926
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- Prest926
- Molecular formula
- C21H23NO4S
- CAS registry number
- 81110-73-8
- InChIKey
- ODUOJXZPIYUATO-UHFFFAOYSA-N
- Libraries
- Prestwick
Stored SMILES
CC(=O)SCC(Cc1ccccc1)C(=O)NCC(=O)OCc1ccccc1Matched external records: PubChem 107751
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ABCB11 · Bile salt export pump | ChEMBL | MDL1 YLR188W (ortholog_many2many); MDL2 YPL270W (ortholog_many2many) |
| Cacna1c · Voltage-dependent L-type calcium channel subunit alpha-1C | ChEMBL | CCH1 YGR217W (ortholog_one2many) |
| CNR1 · Cannabinoid receptor 1 | ChEMBL | No stored yeast mapping |
| NR1H2 · Oxysterols receptor LXR-beta | ChEMBL | No stored yeast mapping |
| NR1H3 · Oxysterols receptor LXR-alpha | ChEMBL | No stored yeast mapping |
| NR1I2 · Nuclear receptor subfamily 1 group I member 2 | ChEMBL | No stored yeast mapping |
| NR1I3 · Nuclear receptor subfamily 1 group I member 3 | ChEMBL | No stored yeast mapping |
| NR3C1 · Glucocorticoid receptor | ChEMBL | No stored yeast mapping |
| OPRK1 · Kappa-type opioid receptor | ChEMBL | No stored yeast mapping |
| PPARA · Peroxisome proliferator-activated receptor alpha | ChEMBL | No stored yeast mapping |
| RARG · Retinoic acid receptor gamma | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Racecadotril research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.