ChemGrid

CHEMGRID MOLECULE CARD

Cloxacillin sodium salt

Cloxacillin sodium salt in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

Prest916

Explore activity & SONAR
Chemical structure of Cloxacillin sodium salt
Stored molecular structure
3Screened assays
0Significant assay responses
2Source-labelled target records

Identity and chemistry

ChemGrid identifier
Prest916
Molecular formula
C19ClH17N3NaO5S
CAS registry number
642-78-4
InChIKey
SCLZRKVZRBKZCR-UHFFFAOYSA-M
Libraries
Prestwick
Other recorded names
Sodium 6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Stored SMILES[Na+].[O-]C(=O)C1N2C(SC1(C)C)C(NC(=O)c1c(C)onc1c1ccccc1Cl)C2=O

Matched external records: PubChem 23699856

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
CruzipainChEMBLNo stored yeast mapping
HPGD · 15-hydroxyprostaglandin dehydrogenase [NAD(+)]ChEMBLAYR1 YIL124W (ortholog_one2one)

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete Cloxacillin sodium salt research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.