CHEMGRID MOLECULE CARD
Iohexol
Iohexol in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
Prest802
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- Prest802
- Molecular formula
- C19H26I3N3O9
- CAS registry number
- 66108-95-0
- InChIKey
- NTHXOOBQLCIOLC-UHFFFAOYSA-N
- Libraries
- Prestwick
Stored SMILES
CC(=O)N(CC(O)CO)c1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c1IMatched external records: PubChem 3730
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ADRB1 · Beta-1 adrenergic receptor | ChEMBL | No stored yeast mapping |
| ADRB2 · Beta-2 adrenergic receptor | ChEMBL | No stored yeast mapping |
| ATAD5 · ATPase family AAA domain-containing protein 5 | ChEMBL | No stored yeast mapping |
| Cacna1c · Voltage-dependent L-type calcium channel subunit alpha-1C | ChEMBL | CCH1 YGR217W (ortholog_one2many) |
| CHRNA4 · Neuronal acetylcholine receptor subunit alpha-4 | ChEMBL | No stored yeast mapping |
| Gabra1 · Gamma-aminobutyric acid receptor subunit alpha-1 | ChEMBL | No stored yeast mapping |
| GMNN · Geminin | ChEMBL | No stored yeast mapping |
| Grin1 · Glutamate receptor ionotropic, NMDA 1 | ChEMBL | No stored yeast mapping |
| KCNH2 · Voltage-gated inwardly rectifying potassium channel KCNH2 | ChEMBL | No stored yeast mapping |
| SLC6A3 · Sodium-dependent dopamine transporter | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Iohexol research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.