CHEMGRID MOLECULE CARD
Cisapride
Cisapride in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
Prest786
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- Prest786
- Molecular formula
- C23ClFH29N3O4
- CAS registry number
- 81098-60-4
- InChIKey
- DCSUBABJRXZOMT-UHFFFAOYSA-N
- Libraries
- Prestwick
- Other recorded names
- Cisapride (USP/INN)
Stored SMILES
COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c1cc(Cl)c(N)cc1OCMatched external records: PubChem 2769
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ADRA1A · Adrenergic receptor alpha-1 | ChEMBL | No stored yeast mapping |
| Adra1a · Alpha-1A adrenergic receptor | ChEMBL | No stored yeast mapping |
| Adra1b · Alpha-1B adrenergic receptor | ChEMBL | No stored yeast mapping |
| Adra2a · Alpha-2A adrenergic receptor | ChEMBL | No stored yeast mapping |
| HTR2A · 5-hydroxytryptamine receptor 2A | ChEMBL | No stored yeast mapping |
| HTR2B · Serotonin 2 (5-HT2) receptor | ChEMBL | No stored yeast mapping |
| HTR4 · 5-hydroxytryptamine receptor 4 | ChEMBL | No stored yeast mapping |
| KCNH2 · Voltage-gated inwardly rectifying potassium channel KCNH2 | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Cisapride research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.