CHEMGRID MOLECULE CARD

Diphemanil methylsulfate

Diphemanil methylsulfate in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

Prest522

Explore activity & SONAR

Chemical structure of Diphemanil methylsulfate — Stored molecular structure

3Screened assays

0Significant assay responses

4Source-labelled target records

Identity and chemistry

ChemGrid identifier: Prest522
Molecular formula: C21H27NO4S
CAS registry number: 62-97-5
InChIKey: BREMLQBSKCSNNH-UHFFFAOYSA-M
Libraries: Prestwick
Other recorded names: Diphemanil methyl sulfate

Stored SMILES

[O-]S(=O)(=O)OC.C[N+]1(C)CCC(CC1)=C(c1ccccc1)c1ccccc1

Matched external records: PubChem 6126

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

Target	Source	Yeast ORF / orthologue
ampC · Beta-lactamase	ChEMBL	No stored yeast mapping
CBX1 · Chromobox protein homolog 1	ChEMBL	No stored yeast mapping
GMNN · Geminin	ChEMBL	No stored yeast mapping
rep · Replicase polyprotein 1ab	ChEMBL	No stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete Diphemanil methylsulfate research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.