CHEMGRID MOLECULE CARD
Hydrocotarnine hydrobromide
Hydrocotarnine hydrobromide in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
Prest267
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- Prest267
- Molecular formula
- BrC12H16NO3
- CAS registry number
- 5985-00-2
- InChIKey
- VMLDPXIOBIJNAW-UHFFFAOYSA-N
- Libraries
- Prestwick
- Other recorded names
- Hydrocotarnine Hydrobromide
Stored SMILES
Br.COc1c2CN(C)CCc2cc2OCOc21Matched external records: PubChem 6419942
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ache · Acetylcholinesterase | ChEMBL | No stored yeast mapping |
| ampC · Beta-lactamase | ChEMBL | No stored yeast mapping |
| BCHE · Cholinesterase | ChEMBL | No stored yeast mapping |
| DRD3 · D(3) dopamine receptor | ChEMBL | No stored yeast mapping |
| GMNN · Geminin | ChEMBL | No stored yeast mapping |
| Htr2a · 5-hydroxytryptamine receptor 2A | ChEMBL | No stored yeast mapping |
| IDH1 · Isocitrate dehydrogenase [NADP] cytoplasmic | ChEMBL | IDP1 YDL066W (ortholog_many2many); IDP2 YLR174W (ortholog_many2many); IDP3 YNL009W (ortholog_many2many) |
| OPRM1 · Mu-type opioid receptor | ChEMBL | No stored yeast mapping |
| TDP1 · Tyrosyl-DNA phosphodiesterase 1 | ChEMBL | TDP1 YBR223C (ortholog_one2one) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Hydrocotarnine hydrobromide research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.