CHEMGRID MOLECULE CARD
Antipyrine
Antipyrine in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
Prest26
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- Prest26
- Molecular formula
- C11H12N2O
- CAS registry number
- 60-80-0
- InChIKey
- VEQOALNAAJBPNY-UHFFFAOYSA-N
- Libraries
- Prestwick
Stored SMILES
CN1N(C(=O)C=C1C)c1ccccc1Matched external records: PubChem 2206
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ATAD5 · ATPase family AAA domain-containing protein 5 | ChEMBL | No stored yeast mapping |
| CBX1 · Chromobox protein homolog 1 | ChEMBL | No stored yeast mapping |
| FAAH · Fatty-acid amide hydrolase 1 | ChEMBL | SCS7 YMR272C (ortholog_one2one) |
| NAPRT · Nicotinate phosphoribosyltransferase | ChEMBL | NPT1 YOR209C (ortholog_one2many) |
| NFE2L2 · Nuclear factor erythroid 2-related factor 2 | ChEMBL | No stored yeast mapping |
| NR3C1 · Glucocorticoid receptor | ChEMBL | No stored yeast mapping |
| PPARD · Peroxisome proliferator-activated receptor delta | ChEMBL | No stored yeast mapping |
| SLC22A1 · Solute carrier family 22 member 1 | ChEMBL | PHO84 YML123C (ortholog_one2many) |
| Slc22a6 · Solute carrier family 22 member 6 | ChEMBL | PHO84 YML123C (ortholog_one2many) |
| THRB · Thyroid hormone receptor beta | ChEMBL | No stored yeast mapping |
| USP1 · Ubiquitin carboxyl-terminal hydrolase 1 | ChEMBL | UBP13 YBL067C (ortholog_many2many); UBP9 YER098W (ortholog_many2many); UBP8 YMR223W (ortholog_many2many); UBP2 YOR124C (ortholog_many2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Antipyrine research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.