CHEMGRID MOLECULE CARD
Flufenamic acid
Flufenamic acid in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
Prest220
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- Prest220
- Molecular formula
- C14F3H10NO2
- CAS registry number
- 530-78-9
- InChIKey
- LPEPZBJOKDYZAD-UHFFFAOYSA-N
- Libraries
- Prestwick
- Other recorded names
- Flufenamic Acid
Stored SMILES
OC(=O)c1ccccc1Nc1cccc(c1)C(F)(F)FMatched external records: PubChem 3371
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| AKR1B10 · Aldo-keto reductase family 1 member B10 | ChEMBL | AAD3 YCR107W (ortholog_many2many); YDL124W (ortholog_many2many); AAD4 YDL243C (ortholog_many2many); YPR1 YDR368W (ortholog_many2many); AAD10 YJR155W (ortholog_many2many); YMR041C (ortholog_many2many); AAD14 YNL331C (ortholog_many2many); AAD15 YOL165C (ortholog_many2many); GCY1 YOR120W (ortholog_many2many) |
| AKR1C2 · Aldo-keto reductase family 1 member C2 | ChEMBL | AAD3 YCR107W (ortholog_many2many); YDL124W (ortholog_many2many); AAD4 YDL243C (ortholog_many2many); YPR1 YDR368W (ortholog_many2many); AAD10 YJR155W (ortholog_many2many); YMR041C (ortholog_many2many); AAD14 YNL331C (ortholog_many2many); AAD15 YOL165C (ortholog_many2many); GCY1 YOR120W (ortholog_many2many) |
| AKR1C3 · Aldo-keto reductase family 1 member C3 | ChEMBL | AAD3 YCR107W (ortholog_many2many); YDL124W (ortholog_many2many); AAD4 YDL243C (ortholog_many2many); YPR1 YDR368W (ortholog_many2many); AAD10 YJR155W (ortholog_many2many); YMR041C (ortholog_many2many); AAD14 YNL331C (ortholog_many2many); AAD15 YOL165C (ortholog_many2many); GCY1 YOR120W (ortholog_many2many) |
| CHRM1 · Muscarinic acetylcholine receptor M1 | ChEMBL | No stored yeast mapping |
| HRH1 · Histamine H1 receptor | ChEMBL | PRP22 YER013W (ortholog_one2one) |
| HTR2A · 5-hydroxytryptamine receptor 2A | ChEMBL | No stored yeast mapping |
| LMNA · Prelamin-A/C | ChEMBL | No stored yeast mapping |
| NAPRT · Nicotinate phosphoribosyltransferase | ChEMBL | NPT1 YOR209C (ortholog_one2many) |
| PTGS2 · Prostaglandin G/H synthase 2 | ChEMBL | No stored yeast mapping |
| TAS2R14 · Taste receptor type 2 member 14 | ChEMBL | No stored yeast mapping |
| TSHR · Thyrotropin receptor | ChEMBL | No stored yeast mapping |
| TTR · Transthyretin | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Flufenamic acid research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.