CHEMGRID MOLECULE CARD
Risperidone
Risperidone in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
Prest1298
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- Prest1298
- Molecular formula
- C23FH27N4O2
- CAS registry number
- 106266-06-2
- InChIKey
- RAPZEAPATHNIPO-UHFFFAOYSA-N
- Libraries
- Prestwick
Stored SMILES
CC1N=C2CCCCN2C(=O)C=1CCN1CCC(CC1)c1noc2cc(F)ccc21Matched external records: PubChem 5073
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Adra1a · Alpha-1A adrenergic receptor | ChEMBL | No stored yeast mapping |
| Adra1b · Adrenergic receptor alpha-1 | ChEMBL | No stored yeast mapping |
| Adra1b · Alpha-1B adrenergic receptor | ChEMBL | No stored yeast mapping |
| ADRA2C · Alpha-2C adrenergic receptor | ChEMBL | No stored yeast mapping |
| DRD2 · D(2) dopamine receptor | ChEMBL | No stored yeast mapping |
| Htr2a · 5-hydroxytryptamine receptor 2A | ChEMBL | No stored yeast mapping |
| Htr2b · Serotonin 2 (5-HT2) receptor | ChEMBL | No stored yeast mapping |
| HTR7 · 5-hydroxytryptamine receptor 7 | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Risperidone research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.