CHEMGRID MOLECULE CARD
Milrinone
Milrinone in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
Prest1256
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- Prest1256
- Molecular formula
- C12H9N3O
- CAS registry number
- 78415-72-2
- InChIKey
- PZRHRDRVRGEVNW-UHFFFAOYSA-N
- Libraries
- Prestwick
Stored SMILES
CC1NC(=O)C(=CC=1c1ccncc1)C#NMatched external records: PubChem 4197
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Phosphodiesterase 3A | ChEMBL | No stored yeast mapping |
| ampC · Beta-lactamase | ChEMBL | No stored yeast mapping |
| BLM · RecQ-like DNA helicase BLM | ChEMBL | SGS1 YMR190C (ortholog_one2one) |
| PDE3A · cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A | ChEMBL | No stored yeast mapping |
| PDE3A · Phosphodiesterase 3 | ChEMBL | No stored yeast mapping |
| PDE3B · cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B | ChEMBL | No stored yeast mapping |
| PDE3B · Phosphodiesterase 3B | ChEMBL | No stored yeast mapping |
| PDE5A · cGMP-specific 3',5'-cyclic phosphodiesterase | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Milrinone research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.