ChemGrid

CHEMGRID MOLECULE CARD

Imidurea

Imidurea in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

Prest1234

Explore activity & SONAR
Chemical structure of Imidurea
Stored molecular structure
3Screened assays
0Significant assay responses
6Source-labelled target records

Identity and chemistry

ChemGrid identifier
Prest1234
Molecular formula
C11H16N8O8
CAS registry number
39236-46-9
InChIKey
ZCTXEAQXZGPWFG-UHFFFAOYSA-N
Libraries
Prestwick
Other recorded names
Imidazolidinyl Urea
Stored SMILESOCN1C(NC(=O)NCNC(=O)NC2N(CO)C(=O)NC2=O)C(=O)NC1=O

Matched external records: PubChem 38258

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
CBX1 · Chromobox protein homolog 1ChEMBLNo stored yeast mapping
HDAC6 · Protein deacetylase HDAC6ChEMBLHDA1 YNL021W (ortholog_one2one)
pol · Human immunodeficiency virus type 1 integraseChEMBLNo stored yeast mapping
RAN · GTP-binding nuclear protein Ran/Importin subunit beta-1/Snurportin-1ChEMBLGSP1 YLR293C (ortholog_one2many); GSP2 YOR185C (ortholog_one2many)
rep · Replicase polyprotein 1abChEMBLNo stored yeast mapping
SAMHD1 · Deoxynucleoside triphosphate triphosphohydrolase SAMHD1ChEMBLNo stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete Imidurea research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.