CHEMGRID MOLECULE CARD
Flucytosine
Flucytosine in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
Prest1223
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- Prest1223
- Molecular formula
- C4FH4N3O
- CAS registry number
- 2022-85-7
- InChIKey
- XRECTZIEBJDKEO-UHFFFAOYSA-N
- Libraries
- Prestwick
Stored SMILES
NC1=NC(=O)NC=C1FMatched external records: PubChem 3366
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ATP-dependent molecular chaperone HSP82 | ChEMBL | No stored yeast mapping |
| CNA1 · Serine/threonine-protein phosphatase | ChEMBL | PPH21 YDL134C (ortholog_many2many); PPH22 YDL188C (ortholog_many2many) |
| NS1 · Nonstructural protein 1 | ChEMBL | No stored yeast mapping |
| POLI · DNA polymerase iota | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Flucytosine research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.