CHEMGRID MOLECULE CARD
Clotrimazole
Clotrimazole in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
Prest120
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- Prest120
- Molecular formula
- C22ClH17N2
- CAS registry number
- 23593-75-1
- InChIKey
- VNFPBHJOKIVQEB-UHFFFAOYSA-N
- Libraries
- Prestwick
Stored SMILES
Clc1ccccc1C(n1ccnc1)(c1ccccc1)c1ccccc1Matched external records: PubChem 2812
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| cyp121 · Mycocyclosin synthase | ChEMBL | No stored yeast mapping |
| CYP17A1 · Steroid 17-alpha-hydroxylase/17,20 lyase | ChEMBL | No stored yeast mapping |
| CYP19A1 · Aromatase | ChEMBL | No stored yeast mapping |
| CYP2C19 · Cytochrome P450 2C19 | ChEMBL | DIT2 YDR402C (ortholog_one2many) |
| CYP2C9 · Cytochrome P450 2C9 | ChEMBL | No stored yeast mapping |
| CYP3A4 · Cytochrome P450 3A4 | ChEMBL | No stored yeast mapping |
| KCNN4 · Intermediate conductance calcium-activated potassium channel protein 4 | ChEMBL | No stored yeast mapping |
| LMNA · Prelamin-A/C | ChEMBL | No stored yeast mapping |
| NR1I3 · Nuclear receptor subfamily 1 group I member 3 | ChEMBL | No stored yeast mapping |
| TBXAS1 · Thromboxane-A synthase | ChEMBL | No stored yeast mapping |
| cyp121 · Mycocyclosin synthase | ChEMBL analogue | No stored yeast mapping |
| CYP17A1 · Steroid 17-alpha-hydroxylase/17,20 lyase | ChEMBL analogue | No stored yeast mapping |
| CYP19A1 · Aromatase | ChEMBL analogue | No stored yeast mapping |
| CYP2C19 · Cytochrome P450 2C19 | ChEMBL analogue | DIT2 YDR402C (ortholog_one2many) |
| CYP2C9 · Cytochrome P450 2C9 | ChEMBL analogue | No stored yeast mapping |
| CYP3A4 · Cytochrome P450 3A4 | ChEMBL analogue | No stored yeast mapping |
| KCNN4 · Intermediate conductance calcium-activated potassium channel protein 4 | ChEMBL analogue | No stored yeast mapping |
| LMNA · Prelamin-A/C | ChEMBL analogue | No stored yeast mapping |
| NR1I3 · Nuclear receptor subfamily 1 group I member 3 | ChEMBL analogue | No stored yeast mapping |
| TBXAS1 · Thromboxane-A synthase | ChEMBL analogue | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Clotrimazole research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.