CHEMGRID MOLECULE CARD
Chrysin
Chrysin in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
Prest1131
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- Prest1131
- Molecular formula
- C15H10O4
- CAS registry number
- 480-40-0
- InChIKey
- RTIXKCRFFJGDFG-UHFFFAOYSA-N
- Libraries
- Prestwick
Stored SMILES
Oc1cc(O)c2C(=O)C=C(Oc2c1)c1ccccc1Matched external records: PubChem 5281607
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| AKR1B1 · Aldo-keto reductase family 1 member B1 | ChEMBL | AAD3 YCR107W (ortholog_many2many); AAD4 YDL243C (ortholog_many2many); YPR1 YDR368W (ortholog_many2many); AAD10 YJR155W (ortholog_many2many); AAD14 YNL331C (ortholog_many2many); AAD15 YOL165C (ortholog_many2many); GCY1 YOR120W (ortholog_many2many) |
| CA12 · Carbonic anhydrase 12 | ChEMBL | No stored yeast mapping |
| CA4 · Carbonic anhydrase 4 | ChEMBL | No stored yeast mapping |
| CA7 · Carbonic anhydrase 7 | ChEMBL | No stored yeast mapping |
| CBR1 · Carbonyl reductase [NADPH] 1 | ChEMBL | YIR035C (ortholog_many2many); YIR036C (ortholog_many2many) |
| CYP19A1 · Aromatase | ChEMBL | No stored yeast mapping |
| CYP1A2 · Cytochrome P450 1A2 | ChEMBL | No stored yeast mapping |
| CYP1B1 · Cytochrome P450 1B1 | ChEMBL | No stored yeast mapping |
| CYP2C19 · Cytochrome P450 2C19 | ChEMBL | DIT2 YDR402C (ortholog_one2many) |
| HDAC6 · Protein deacetylase HDAC6 | ChEMBL | HDA1 YNL021W (ortholog_one2one) |
| XDH · Xanthine dehydrogenase/oxidase | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Chrysin research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.