CHEMGRID MOLECULE CARD
Ebselen
Ebselen in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
Prest1057
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- Prest1057
- Molecular formula
- C13H9NOSe
- CAS registry number
- 60940-34-3
- InChIKey
- DYEFUKCXAQOFHX-UHFFFAOYSA-N
- Libraries
- Prestwick
Stored SMILES
O=C1N([Se]c2ccccc12)c1ccccc1Matched external records: PubChem 3194
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ALOX15 · Polyunsaturated fatty acid lipoxygenase ALOX15 | ChEMBL | No stored yeast mapping |
| blaNDM-1 · Metallo-beta-lactamase type 2 | ChEMBL | No stored yeast mapping |
| gag · Structural capsid protein | ChEMBL | No stored yeast mapping |
| GALE · UDP-glucose 4-epimerase | ChEMBL | GAL10 YBR019C (ortholog_one2one) |
| HDAC2 · Histone deacetylase 2 | ChEMBL | No stored yeast mapping |
| IDE · Insulin-degrading enzyme | ChEMBL | No stored yeast mapping |
| lef · Lethal factor | ChEMBL | No stored yeast mapping |
| LMNA · Prelamin-A/C | ChEMBL | No stored yeast mapping |
| rep · Replicase polyprotein 1ab | ChEMBL | No stored yeast mapping |
| tcdB · Toxin B | ChEMBL | No stored yeast mapping |
| TDP1 · Tyrosyl-DNA phosphodiesterase 1 | ChEMBL | TDP1 YBR223C (ortholog_one2one) |
| ALOX15 · Polyunsaturated fatty acid lipoxygenase ALOX15 | ChEMBL analogue | No stored yeast mapping |
| blaNDM-1 · Metallo-beta-lactamase type 2 | ChEMBL analogue | No stored yeast mapping |
| gag · Structural capsid protein | ChEMBL analogue | No stored yeast mapping |
| GALE · UDP-glucose 4-epimerase | ChEMBL analogue | GAL10 YBR019C (ortholog_one2one) |
| HDAC2 · Histone deacetylase 2 | ChEMBL analogue | No stored yeast mapping |
| IDE · Insulin-degrading enzyme | ChEMBL analogue | No stored yeast mapping |
| lef · Lethal factor | ChEMBL analogue | No stored yeast mapping |
| LMNA · Prelamin-A/C | ChEMBL analogue | No stored yeast mapping |
| rep · Replicase polyprotein 1ab | ChEMBL analogue | No stored yeast mapping |
| tcdB · Toxin B | ChEMBL analogue | No stored yeast mapping |
| TDP1 · Tyrosyl-DNA phosphodiesterase 1 | ChEMBL analogue | TDP1 YBR223C (ortholog_one2one) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Ebselen research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.