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CHEMGRID MOLECULE CARD

3-nitroimidazo[1,2-a]pyridine

3-nitroimidazo[1,2-a]pyridine in ChemGrid: 50 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

NRB 01107

Explore activity & SONAR
Chemical structure of 3-nitroimidazo[1,2-a]pyridine
Stored molecular structure
50Screened assays
0Significant assay responses
3Source-labelled target records

Identity and chemistry

ChemGrid identifier
NRB 01107
Molecular formula
C7H5N3O2
InChIKey
WYDBFRQNRYIZSL-UHFFFAOYSA-N
Libraries
Maybridge1000
Other recorded names
3-Nitroimidazo[1,2-a]pyridine
Stored SMILES[O-][N+](=O)c1cnc2C=CC=Cn21

Matched external records: PubChem 259819

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

50 measurements across 50 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
EHMT2 · Histone-lysine N-methyltransferase EHMT2ChEMBLSET2 YJL168C (ortholog_many2many)
MBNL1 · Muscleblind-like protein 1ChEMBLNo stored yeast mapping
NFE2L2 · Nuclear factor erythroid 2-related factor 2ChEMBLNo stored yeast mapping

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete 3-nitroimidazo[1,2-a]pyridine research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.