CHEMGRID MOLECULE CARD
2-[(2,5-dichloro-1-benzothiophen-3-yl)methyl]-1,3-thiazole-4-carbohydrazide
2-[(2,5-dichloro-1-benzothiophen-3-yl)methyl]-1,3-thiazole-4-carbohydrazide in ChemGrid: 71 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
MWP 00307
Explore activity & SONARIdentity and chemistry
- ChemGrid identifier
- MWP 00307
- Molecular formula
- C13Cl2H9N3OS2
- InChIKey
- JEUOZRHTLUPANV-UHFFFAOYSA-N
- Libraries
- Maybridge, Bioactive
- Other recorded names
- 2-[(2,5-Dichloro-1-benzothiophen-3-yl)methyl]-1,3-thiazole-4-carbohydrazide
Stored SMILES
NNC(=O)c1csc(Cc2c(Cl)sc3ccc(Cl)cc23)n1Matched external records: PubChem 2824155
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
71 measurements across 71 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| IDH1 · Isocitrate dehydrogenase [NADP] cytoplasmic | ChEMBL | IDP1 YDL066W (ortholog_many2many); IDP2 YLR174W (ortholog_many2many); IDP3 YNL009W (ortholog_many2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 2-[(2,5-dichloro-1-benzothiophen-3-yl)methyl]-1,3-thiazole-4-carbohydrazide research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.